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Exploiting Cytokine Biology and Strategies for Using Non-TNF Agents in Clinical Practice Training

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This education is accredited: RACGP 2 CPD, ACRRM 1 CME PD.

Overview:
Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting 1% of the population, which if left untreated can lead to joint destruction and a host of systemic complications. This module explores novel treatment approaches for RA through newly developed medications including IL-6 inhibitors, and their effectiveness in clinical practice.

Learning Objectives:
Upon completion of this module the participant should be able to:

  • Describe the role of cytokines, particularly IL-6, in the pathogenesis and treatment of RA
  • Identify patients with RA in whom an IL-6 inhibitor, or other non-TNFi therapy, may be an appropriate strategy
  • Describe new and emerging biologic therapies for RA
  • Integrate strategies to address patient safety concerns and adverse events associated with TNF inhibitors


Disclosure of Conflicts of Interest
Roy Fleischmann, MD, MACR
Consultant/Advisor: Amgen Inc, AbbVie Inc, Bristol-Myers Squibb Company, Janssen Pharmaceutical Companies, Pfizer Inc, Sanofi-Regeneron, UCB Inc.
Grant/Research Support: Amgen Inc, AbbVie Inc, Bristol-Myers Squibb Company, Janssen Pharmaceutical Companies, Pfizer Inc, Sanofi-Regeneron, UCB Inc.
Speakers' Bureau: Pfizer Inc.

Peter Nash, MD
Has no financial relationships to disclose.

Non-faculty:
Christina M. Ohnsman, MD; Jessica Marshall, PhD; Lou Settembrino; Sandy Breslow; and Alison Kemp; hereby state that neither they nor their spouse/life partner have had any financial relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.


This activity has been supported by an independent educational grant from Genzyme, a Sanofi Company and Regeneron Pharmaceuticals.

Jointly provided by the Elsevier Office of Continuing Medical Education, ASiM, In Vivo Academy Limited, and Reed Medical Education.

Components
Exploiting Cytokine Biology - education
Exploiting Cytokine Biology - evaluation